Induction of chemiluminescence in human polymorphonuclear leukocytes by the calcium ionophore A23187
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چکیده
منابع مشابه
Calcium-dependent shortening of fibroblasts induced by the ionophore, A23187.
Attached, spread, chick heart fibroblasts were induced to shorten by treatment with the ionophore, A23187. The shortening resulted from the retraction of the leading lamellae and other major cell processes. The response was dependent on external calcium with a threshold close to, and a maximal effect at, physiological concentrations. The shortening was also induced in Colcemid-treated cells and...
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Human peripheral blood leukocytes (PMN) are induced to release lysosomal enzymes by the calcium ionophore A23187 in the presence but not the absence of extracellular Ca++. Whereas secretion induced by particulate or immune stimuli is accompanied by an increase in visible microtubules and is inhibitable by colchicine, secretion induced by A23187 and Ca++ was not accompanied by an increase in mic...
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Chemiluminescence (CL) is an index of both the generation of and reactions mediated by Cv and 'O2. The tumor promoter, 12-O-tetradecanoylphorbol-13-acetate (TPA), is a potent stim ulator of CL by human polymorphonuclear leukocytes; treat ment with TPA (100 ng/ml) provokes a CL response that peaks within five min and persists for over 30 min. The response is proportional to concentration over th...
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ژورنال
عنوان ژورنال: FEBS Letters
سال: 1978
ISSN: 0014-5793
DOI: 10.1016/0014-5793(78)80984-3